The Biologics Control Act ofalso known as the Virus-Toxin was the first law that implemented federal regulations of biological products such as vaccines in the United States.
Biologics control is now under the supervision of the U. When the large scale production of vaccines began in the late 19th century, the United States had no government regulations on biological products.
Louis, Missouri after being given a diphtheria anti-toxin. Investigations found that the St. Louis Board of Health produced the contaminated vaccine using the blood of a horse infected with tetanus. While the infected horse, Jimwas killed, the Board of Health continued to use the serum to treat diphtheria. It was later discovered that 12 other children had died from the same contaminated vaccines in St.